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To mechanistically dissect how GGCT remodels TCA cycle flux, we first employed [U- 13 C]glutamine isotope tracing to map the rerouting of Gln metabolic pathways

This research shows that dietary supplements can disrupt mucusbacterial interactions, promoting gut inflammation

In macrophages, S-palmitoylation of NOD1/2, catalyzed by ZDHHC5, is required for their membrane localization to bacterium-containing endosomes and activation of downstream NF-B and MAPK signaling ( 131 )

These results suggest that epitalon could help protect the brain, improve memory, and slow down age-related mental decline, making it a promising tool for supporting cognitive health as we age

P2Y6 receptor mediates colonic NaCl secretion via differential activation of cAMP-mediated transport